HAUPPAUGE, N.Y., Nov. 9, 2023 /PRNewswire/ — Bio-Botanica, Inc., ® the one American company that has manufactured botanical extracts under one family for more than 50 years, has revealed the results of clinical trials indicating its proprietary botanical extract ingredient, Puresterol® (Pueraria mirifica), showed positive effects on the reduction of wrinkles when used in a face serum.
Pueraria mirifica grows only in the rich soils of the high-altitude rainforests of Thailand and has been used by the Thais for a millennium as a rejuvenator and revitalizer to help offset some of the effects of aging. Puresterol®, developed by Bio-Botanica, is the only patented, specially processed and highly active compound of Pueraria mirifica available in the market today (US Patent # 7,658,955, 2023).
A third-party contract research organization (CRO) conducted clinical trials of Puresterol® in two different serum formulations under sponsorship by Bio-Botanica. In each trial, 21 subjects in different groups applied a serum in the morning and night for 28 days. The CRO used a state-of-the-art 3D structured-light scanner and software to precisely measure the area, length, and depth of crow’s feet and forehead wrinkles at day 0 and day 28. In addition, subjects were asked to evaluate their assessment of their treatment.
The first, placebo-controlled trial indicated Puresterol® in a serum had a statistically significant greater reduction of the depth of Crow’s feet wrinkles when compared to placebo (p